Best Practices for Developing AI Agents: A Developer’s Guide

Learn how to build smarter, more effective AI agents with Mayfly Ventures’ guide to best practices. From user-focused design to leveraging low-code tools, we help developers thrive in the AI revolution.

2025 feels like the dawn of the AI Agent revolution—a time when software isn’t just smart, but autonomous enough to carry out tasks, make decisions, and improve itself with minimal human input. If you’re a developer or founder looking to get ahead of the curve, building AI agents is one of the most exciting frontiers in tech right now.

Whether you’re a seasoned engineer or diving into AI for the first time, this guide will outline best practices for developing AI agents that don’t just work but thrive in real-world applications.

Geo Founding Partner of Mayfly Ventures

1. Start with the Problem, Not the Technology

The most common pitfall for developers is getting swept up in the tech and forgetting the end user. Before diving into building, identify a specific problem or inefficiency your AI agent will solve.

For example, Fairgo—an AI HR agent—was built to streamline hiring processes by automating initial candidate interviews and recommendations. Its success lies in its laser focus on solving a pain point for recruiters, not just showcasing the capabilities of AI.

Tip: Spend time talking to potential users. Understand their workflows and pain points deeply before writing a single line of code.

2. Choose the Right Foundation

Not all AI agents are built the same, and your choice of foundational model matters. Popular options include:

  • OpenAI’s GPT models for general-purpose natural language processing.
  • Relevance AI for domain-specific data workflows.

Understand what your agent needs to achieve. For complex, industry-specific tasks, you may need fine-tuned models. For broader, text-based applications, pre-trained models may suffice.

Tip: Keep scalability in mind. Choose a platform that allows easy iteration and adaptation as your agent evolves.

3. Embrace No-Code and Low-Code Tools

AI agents don’t have to cost millions to build. Platforms like Bubble.io and Flutterflow make it easier than ever to create functional prototypes without deep technical expertise.

At Mayfly Ventures, we’ve seen startups validate their AI agents in weeks using low-code tools, saving tens of thousands in development costs. Your first iteration doesn’t need to be perfect—it needs to be viable.

4. Prioritize Context and Fine-Tuning

The power of AI agents lies in their ability to understand context. Generic models like GPT-4 are powerful but often lack the industry-specific nuance required for vertical AI agents.

Fine-tuning your model with domain-specific data is key. For instance, training a sales AI agent on scripts, common objections, and CRM data will make it far more effective than relying solely on out-of-the-box models.

Tip: Use small-scale pilot programs to gather data and fine-tune incrementally based on real-world feedback.

5. Build for Explainability and Trust

AI agents operate in environments where trust is non-negotiable. Whether it’s healthcare, finance, or customer support, users need to understand how and why your agent makes decisions.

To build trust:

  • Incorporate explainable AI techniques.
  • Provide detailed logs or summaries of decisions made by your agent.
  • Focus on transparency, especially when handling sensitive data.

6. Integrate Seamlessly into Existing Systems

Towards a European large-scale initiative on Artificial Intelligence - CEPS

An AI agent’s value lies in how well it complements existing workflows. For example, Relevance AI offers APIs that can easily integrate with no-code tools, CRM platforms, and even legacy systems.

Avoid building an AI agent in isolation. Make it compatible with the tools and processes your target users already rely on.

7. Test, Iterate, and Improve

The best AI agents are built through iteration. Launch a minimum viable product (MVP) with a narrow feature set, then gather feedback from users to improve functionality.

Example:

When Mayfly Ventures built VOLI’s AI-powered MVP, the focus was on proving its ability to solve one core problem. Iterative updates, guided by user feedback, led to a robust platform that’s now onboarding enterprise customers.

8. Design for a Human-Agent Collaboration

AI agents don’t replace humans—they amplify them. Design your agent to complement human workflows, not to replace them entirely.

For example:

  • An AI agent in customer support might draft responses for human agents to review, rather than sending them automatically.
  • A sales AI agent could prioritize leads, leaving the final decision-making to a human sales team.

9. Plan for Ethical Use and Compliance

Ethics in AI is no longer optional. Be mindful of potential biases in your model, and ensure compliance with data privacy laws like GDPR or Australia’s Privacy Act.

Proactively address these concerns by:

  • Auditing training data for bias.
  • Allowing users to opt out of data collection.
  • Creating clear policies for how your AI agent operates.

10. Focus on Long-Term Maintainability

The work doesn’t stop once your AI agent is live. Maintenance, updates, and retraining are ongoing processes.

Invest in:

  • Clear documentation for developers and users.
  • Automated monitoring systems to track performance and identify issues.
  • A scalable infrastructure that can handle increased demand.

Conclusion

Developing AI agents isn’t just about building—it’s about solving real problems, iterating based on user feedback, and ensuring long-term usability. Whether you’re a solo founder or part of a venture studio, following these best practices will help you build AI agents that deliver real value and stand out in the market.

At Mayfly Ventures, we specialize in helping founders build scalable AI agents using low-code tools and cutting-edge models like Relevance AI. If you’re ready to turn your idea into reality, let’s talk.

Co-building disruptive AI Agents with industry insiders


AI Agents are set to completely overhaul how industries operate, creating efficiency unlocks well beyond using ChatGPT. We combine our deep expertise in building disruptive AI Agent ventures with industry insiders who see opportunity.

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The Mayfly Approach

It's easy to build an AI agent. We build globally scalable businesses.

We pair our venture building expertise with your industry insights to create ground breaking companies.

We define key product features which unlock immense efficiency, help to craft a viable business model which addresses a sizable market which can be captured by a robust GTM strategy. We then plug you into our investor network to unlock your next stage of growth

We aren't your tech team, we are your venture partners.

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We use validation techniques to ensure we are solving the right problem, with the right solution for the right people to bring products to market which deliver immense value and address clear market demand.

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Our design framework defines the key features needed to deliver on your UVP. Our aim is to create the shortest path possible to deliver our intended value to your users.

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We bring your product to life using the latest AI and software development platforms, optimising for performance, scalability and user delight.

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We design your Go-To-Market strategy which consists of sending the right message, to the right person at the right time in the right way to onboard early adopters to gain insights from.

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Here we define the metrics you should obsess over, create strong feedback mechanisms to collect user feedback to systematically iterate towards product-market fit.

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Vertical AI Agents Could Be 10X Bigger Than SaaS

In the 1980s and 90s, boxed software became a popular way to distribute software, whether it was gaming software, multimedia applications, or office tools. Companies like Microsoft, Adobe, and Corel rose significantly on the back of selling boxed software to millions of consumers and businesses.

In the 2000s, cloud computing and SaaS began their meteoric rise. Digital downloads, cloud-based storage, and computing simplified the process of purchasing and using software. No longer was there a need to buy a physical CD-ROM or transfer files via USB—you could access software within a few clicks.

Microsoft Office 365, for example, eliminated the need for local installation, while companies like Hubspot, Zendesk, Atlassian, and Adobe Creative Cloud revolutionized their respective industries. Today, there are approximately 337 SaaS unicorns, and this number is rapidly growing.

The next major evolution of software is AI Agents which essentially allows companies to have the software and for the software to run itself. This will provide immense time and cost savings for companies which is why many are excited about the AI Agent future.

Mark Zuckerberg,
Facebook

"I think we're going to live in a world where there are 100's of billions of AI agents. Eventually there will be more AI agents than people in the world."

Diana Hu, YC Partner

"The bull case for AI agents to be bigger than Saas, is SaaS still needs people to operate the software. The argument here is with AI agents you don't just need to replace the software, it's going to eat the payroll."

Satya Nadella,
Microsoft CEO

"AI agents will become the primary way we interact with computers in the future. They will be able to understand our needs and preferences, and proactively help us with tasks and decision making."

Bill Gates,
Microsoft

"Agents are not only going to change how everyone interacts with computers. They’re also going to upend the software industry, bringing about the biggest revolution in computing since we went from typing commands to tapping on icons."

Jared Friedman,
YC Partner

"Vertical AI Agents Could Be 10X Bigger Than SaaS. Every SaaS company build some software which a group of people use. The vertical AI equivalent will be the software plus the people."

Dhamesh Shah,
Hubspot CTO

"Last year was all about chat. The way the world looks soon is that we will have hybrid teams that consists of humans and consists of AI agents."

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